Detailed Notes on stem cell treatment
With the concept a far more swift cell cycle is a vital element of pluripotency, reprogramming effectiveness is usually improved. Strategies for bettering pluripotency via manipulation of cell cycle regulators include: overexpression of Cyclin D/Cdk4, phosphorylation of Sox2 at S39 and S253, overexpression of Cyclin A and Cyclin E, knockdown of Rb,